PMOS is a personal health problem


These are Optimizerweekly newspaper sent every Friday from On the edge chief inspector Victoria Song that dissects and discusses new gizmos and potions that swear they will change your life. Choose Optimizer Here.

A few days ago, my esthetician was applying hot wax to my face. The two caterpillars I called eyebrows were very important to keep – as was my mother’s ‘stache. I hate this month’s tradition, but facial hair is such a pain. Hirsutism is probably one of the more noticeable symptoms that has plagued me for the past decade. Until this week, I have been diagnosed with polycystic ovary syndrome (PCOS).

Most of the time, I chat and talk about the weather (it’s hard to have a serious conversation when someone is tearing your hair out). But that day, we spent the whole session talking about how the world’s medical organizations decided this week renaming PCOS to polyendocrine metabolic ovarian syndromeor PMOS.

There are several reasons. Despite the original name, PMOS – which affects about 170 million, or one in eight, women worldwide – usually does not cause ulcers. The modified name better reflects the physiological and metabolic processes involved, not just reproduction. The reality is that this disease can affect multiple organs and is associated with other diseases, such as insulin resistance, type 2 diabetes, obesity, heart disease, and obstructive sleep apnea. According to The New York Timesfocus on the name one the traditional symptom – ovarian cysts – has led to inadequate medical training, poor research funding, delayed diagnosis, and fragmented care for people with PMOS. In my experience, doctors often tell me that PMOS is good and refuse to give treatment unless I want to get pregnant.

As it turns out, my psychic also has PMOS. Except she has cysts, I don’t. I have insulin resistance; they don’t. I suffer a little from hirsutism, while he complained about cystic acne. All of us put on about 60 pounds from nowhere, but managed to control it by intermittent fasting, special diets, and supplementing with milk thistle and myo-inositol, a type of fat that helps increase insulin sensitivity. Metformin – the diabetes drug used to treat PMOS – did nothing for him, while it is a helpful part of my medication along with GLP-1.

I have talked to many of my PMOS sufferers over the years. We are always fascinated by how the same situation can appear in different ways. And although we often exchange tips, I have never heard of a single treatment that works for anyone I’ve ever met with PMOS. Personally, I have spent about 12 years at this point trying to improve mine. This is why I turned to wearables and health technology.

And it’s the first thing I think of every time a health technology company or health care provider suggests a health change.

May is usually when my calendar starts to fill up with meetings and companies about what I’m hitting. It’s the start of a series of conversations about the new items on the docket, where he sees the group changing, and how he thinks about modern health. Of the half a dozen I’ve had so far this year, there’s one thought that keeps coming up: personal health.

All the companies I’ve talked to agree that laughing off useful information from the health care industry is confusing. But I am told over and over again that I am wise of data, the holy grail is personal health – meaning personalized health advice and general advice. A simple example would be if your heart rate fluctuations indicate good recovery, but you had a sleepless night, a wearable device would encourage you to do 20 minutes of vinyasa yoga instead of a long workout. If you keep track of your food, maybe a healthy AI will figure out that the fried broccoli in your lunch is related to medicine and is the cause of your daily battle with sulfur burps. Based on your CGM and blood test data, maybe your fitness tracker will one day tell you what to drink. And that’s itI’ve been told many times, you can have many benefits for your health.

It is an attractive place. Health and very personal. Your genes play a big role in what drugs work for you, what you can expect, and what sports your body is best suited for. I can understand why health care companies, large and small, are excited about this idea. But again, I have to point my journey with PMOS.

A person is looking at daytime stress metrics in the Oura app.

Analyzing what data is most important is always an uphill climb. Branding can help but it requires consistent effort on your part.
Photo by Amelia Holowaty Krales/The Verge

For better or worse, many doctors tell someone with PMOS to try to lose weight. The bottom line is that losing weight often improves, or reduces, symptoms. The only problem is that it’s a catch-22. Weight gain and PMOS are often associated with insulin resistance, which makes “calories in, calories out” very difficult to create because it creates a vicious cycle. Excess insulin causes androgen production, which causes PMOS patients to store more abdominal fat. Research has also shown that patients with PMOS they have low basal metabolic rates. Meaning, all else being equal, they burn fewer calories per day than people without PMOS. This condition can also cause problems in to build lean muscle mass.

I have yet to find a workout or diet that does this. There is no button I can press to change the view or calorie estimate. (This is one reason why I don’t recommend that people put too much effort into targeting energy and fitness.) The same is often true of reproductive technology. When it comes to predicting fertile windows, I usually can’t test this because the algorithms don’t have the tools to deal with hormonal birth control – another popular help for PMOS (and for people with all other types!). Will these things explain how Hormonal oral contraceptives can alter body temperature? Each health care provider has their own method, so you should ask everyone.

Maybe this will happen one day. Wearable technology and to help researchers get new ones agreement among biometric data, especially for reproductive health. But so far, there are very few types of people who deviate from the “standards” that the algorithms are designed for. If you fall into that category, “personal health” is often a list of answers you’ve come up with on your own.

Some of this is a matter of time. Generative AI is still new, and companies are seeing real-time hurdles. Also, the human body remains, for the most part, a mystery. I am hard providing personalized health technology if even medical professionals are distracted by other things. Perhaps worst of all, good science takes a long time, while the push is for technology to move faster. PMOS was first identified in 1935, and in 2026 the name clearly reflects the extent of the problem. (Although the reform took 14 years and more than 50 medical teams.) However, health systems are spreading. now. For some people, this may mean a more straightforward experience because they don’t have a serious medical condition. For many others, it is a situation that is built on a foundation that is constantly changing.

For me, human health technology now means a lot of elbow grease. I have to train the AI ​​trainer. I need to think more about my PMOS episodes and non-alcoholic fatty liver disease. I need to choose the metrics I’ve collected over the years that fit my needs. I have to do independent research and suffer and see several doctors. I have to try and test the available drugs. I spent a lot of time asking the experts a lot of questions and analyzing their answers.

Executive director Victoria Song looks down at the phone's CGM app in the bathroom while standing in front of the window

I spend a good part of every day analyzing data, interpreting the AI ​​trainer’s advice, and what I want is my PMOS under control.
Photo by Amelia Holowaty Krales/The Verge

I’m not trying to rain down on individualized medicine. I’m reasonably confident about some of the health products I’ve been looking at briefly. And there have been many times over the past 12 years when I would have loved this kind of advice. (Who knows, it may save me from listening to a poor doctor who insisted that I take desiccated pig thyroid extract because they misdiagnosed me with hypothyroidism.) I believe that down the line, the health industry will look at “algorithmic systems” to explain various diseases, drugs, and other health issues.

What I’m saying is that the health care industry is starting to put this idea into practice as much as possible now. Like it’s easy to wear a device and ask for AI. And it’s not like that. At least, not as much as you would like – in hindsight, with a little effort on your part.

And for now, I think I’ll do some research on the milk thistle that inspired me.

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